Magnetic Resonance Spectroscopy in the Brain

Magnetic resonance spectroscopy (MRS) is a technique that detects metabolites, such as n-acetyl aspartate, choline-containing compounds, creatine/phosphocreatine, and lactate. Measurements of metabolite ratios provide diagnostic information that adds to that obtained by MRI alone MRS can be valuable in:
– The diagnosis of leukodystrophies and mitochondrial disorders
– Providing prognostic information in neonatal hypoxia/ischemia
– Differentiating among brain tumors, staging, and identifying a suitable biopsy site
– Differentiating between tumor progression and radiation necrosis
In most cases, single voxel MRS is used to obtain chemical information from a region of interest measuring 2x2x2 cm; in multivoxel MR spectroscopic imaging (MSRI), the voxel size is 1x1x1 cm (Radiology Rounds, July 2012 – Volume 10. Issue 7) <<< leia mais >>>

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